In the treatment of acute renal failure without the use of dopamine

According to a meta-analysis of the results showed that in patients with acute renal failure in the application of low-dose treatment is actually dopamine not valid.

U.S. Pennsylvania, the University of Pittsburgh Medical Center, Dr. John A. Kellum Medical News told Reuters in an interview that "the majority of ICU in the treatment of acute renal failure frequently used low-dose dopamine." But when he and another A colleague Janine M. Decker Survey study of 24 patients with 1,019 cases of the information, they found no evidence to support the application of dopamine can be prevented or treated renal failure.

These results show that dopamine on progress or the occurrence of renal failure, the mortality rate and the need for liver benches that Terrace haze ⑽ Postscript Lian Chen Bi-Q-core cough published in the "critical care medicine," the magazine wrote, "Although dopamine in The prevention or treatment of renal failure in null and void, but the drug may still be a relatively safe drug. "


They believe that, in accordance with these findings, the application of low-dose dopamine treatment of renal failure may be unreasonable.


Los Angeles, the University of Southern California School of Pharmacy of Dr. Maria I. Rudis agree with this view. In her comment that the meta-analysis of the recent reports confirm that the Australian and New Zealand intensive care the results of the study. In this large prospective randomized, double-blind trials, 324 cases of renal failure in the ICU patients with 2 μ g / kg / min of dopamine ineffective treatment.

Dr. Rudis concluded, "In the unconfirmed cases of low-dose treatment is not desirable for dopamine."