Can Oral insulin

It is well known that diabetes is mainly because in absolute or relative lack of insulin-induced. Insulin is thus the most physical role of a hypoglycemic agents. Especially for type I diabetes and complications of acute high blood sugar, insulin therapy is used to be. It ketoacidosis, such as the critically ill emergency patients can be said to have "revived" effect.

However, because insulin is a protein, and all other proteins, the oral into the gastrointestinal tract, it was acid and gastrointestinal tract digestive enzymes to digest by the decomposition, which lost its biological activity of insulin. Therefore, since the beginning of the century discovery of insulin has been used only injecting drug delivery. However, various injection methods are more trouble, but also for patients suffering a certain extent. So over the years, many people used to explore ways other than injecting insulin, including oral, inhalation of spray, inhalation powder, intranasal, including clothes, and even absorbed by the vagina or rectum, and other methods. Until this year, before formal approval of inhaled insulin are listed. It is the result of the alveolar lung micro-absorption, will not be damaged, but a result of smoking and respiratory illness, its application to be limited.

Oral drugs are the most commonly used forms, thus oral insulin has been the goal of many domestic and foreign researchers. The idea is to use insulin protection of parcels, so that not a violation of gastrointestinal tract, into the small intestine to be dissolved after the protective film, the human body to absorb insulin. The protection of the election, specifically how to operate, the more difficult and therefore has yet to market.

June-66 in the American Diabetes Association annual meeting, a three articles on oral insulin attention. This is the same product to study in type 2 diabetes the absorption curve, the effect of lowering blood glucose and the impact of C-peptide. And long-acting insulin analogue for the injection of contrast, in individual patients and trial. It is a capsule, as a long-acting insulin and the application of the general dose is 0.33 mg / kg body weight. After its oral insulin bioavailability of injecting the equivalent of 60 percent to 70 percent. From the blood visible in the oral insulin concentration after 30 minutes was the highest. The current trial found no adverse reactions, it does not have low blood sugar reactions, but also without the gastrointestinal tract stimulus.

Although this is a preliminary clinical study, but its bioavailability than in the past to other research results, but also more security and is therefore worthy of further study. According to expert estimates, nearly 12, still can not be listed, but around 2010 is likely to be the official products.

Through the efforts of scientists worldwide, people are heading toward the road to cure diabetes. So to believe in science, strict control of blood sugar, the prognosis is good. Insulin is good medicine, and never will, "addiction"!