about Purpura nephritis

Henoch-Schonlein purpura is systemic damage to small blood vessels as the main basis of pathology, clinical skin to Purpura, hemorrhagic gastroenteritis, arthritis and kidney damage to the characteristics of the syndrome. In allergic purpura patients, about 1 / 3 more kidney damage can occur, the prognosis depends largely on the severity of renal disease, will be allergic purpura caused by kidney damage known as allergic purpura nephritis.

Pathogenesis

The disease often occur in children under 10 years of age, adults (> 20-year-old) rare. Good occurred in the cold season. About 1 / 3 patients bacteria, viruses and other infections pioneer history, but failed to prove that the infection with streptococcus sure relations. About 1 / 4 patients with fish, shrimp allergy or vaccination, drug-related. Most patients with benign, self-limiting process, the majority of patients with proper treatment in a few weeks to recover. However, there are recurrent or persistent few months, a few years, about 50% of patients course repeated attack.

About allergic purpura nephritis in allergic purpura in the incidence of reported mixed, Nantong Medical School Professor Qian Tongsun Statistics reported 2,840 cases at home and abroad, who account for Purpura nephritis 37.6%.

Purpura nephritis clinical performance

(1), renal symptoms including: ① rashes, bleeding and symmetry of distribution. Red rash at the beginning of dot-like, the pressure may disappear, gradually turned into purple hemorrhagic rash, skin slightly uplift table. Rash often symmetry in the distribution of both lower extremities to the ankle, knee around Most of the hip and can be found in the upper limb. Rash can be dissipated into yellow brown. Most cases of rash can have 1 or 2 times of up to three times repeatedly, individual continuous attack for several months or even years. ② joint symptoms, the majority of the migration of multiple joint pain for the features. The knee joint involvement is common, ankle and hands. Symptoms more than a few days faded, not left over from the joint deformation. ③ gastrointestinal symptoms, the most common is abdominal pain, mainly to lower abdomen and Qizhou, paroxysmal colic. Can be accompanied by nausea, vomiting and bloody, occasionally vomit blood. In children can sometimes with intussusception, obstruction and intestinal perforation. ④ other symptoms, such as swollen lymph nodes, hepatosplenomegaly, pulmonary hemorrhage caused by a handful of hemoptysis, hypertensive encephalopathy, or nephritis caused by brain lesions caused by Purpura convulsions, paralysis and coma. (2) kidney symptoms: rash more common in after four to eight weeks, a few of months later. Individual seen before or rash rash after two years. The most common manifestations as isolated hematuria, a national report 1 / 4 to 1 / 2 cases showed gross hematuria. Proteinuria more of a minor, but can also develop into a large number of proteinuria and performance for nephrotic syndrome. There may be a small number of cases of acute renal deterioration. Some patients can have high blood pressure and edema.

Purpura nephritis prevention and care

First of all should avoid contact with the disease induced by the various "unrighteousness of gas" to avoid fish, shrimp, crab, pollen, milk, and so may trigger allergic purpura nephritis diet. Second should pay attention to warm cold, flu prevention and attention to physical exercise and enhance physical fitness, increase body resistance capacity. Again, the sick, to bed rest and avoid excessive Fanlao, restraint房事, Jishi tobacco and alcohol. Catering to rich nutrition, easy to digest, and more potable fresh vegetables, fruit. For Niaoxue patients should Jishi spicy, dry-stimulus and the seafood of, such as the rooster, fish, beef, lamb, goose, and so on, so as not to help heat of the fire, adding to illness. Urine protein, but more attention should be eating high-protein diet, not to prevent virtual meeting.