4/26/08

The joint diabetes medication to be careful

The current treatment of diabetes is still the main dietary restraint, if not sufficient to ease the condition. Choice of drug treatment, a commonly used insulin injection and a sugar-ning, hypoglycemic Ling, glibenclamide, C urea methyl chloride, and other oral hypoglycemic agents, including insulin stronger role, mainly used for heavy patients, oral hypoglycemic agents Used only for light and medium-sized patients.

In addition to master indication, the combination can not be taken lightly, or else they would drop effect, failure, or even aggravate deteriorating condition. Certain drugs has increased its role in blood sugar, such as prednisone, to Yan Song and cortisone acetate, hydrocortisone and dexamethasone, betamethasone, such as training, can increase glycogen yuan, to glucose Increased. If they are combined with hypoglycemic agents, to generate confrontation, to reduce the effect. Also, Furosemide, Lee uric acid, chlorine-thiadiazole, thiazin-dihydrochloride, such as chlorine, can inhibit insulin secretion, increased blood sugar and even coma. Another example chlorine acid, non-Flanagan, Taier Deng, perphenazine, Trifluoperazine, and a security iodine, thyroid stimulating hormone, also have similar circumstances, it is not appropriate combination.

There are women of childbearing age use of estrogen and progesterone oral contraceptives, hypoglycemic agents also down efficiency, the need to switch to other contraceptives. Some drugs and oral hypoglycemic agents or insulin combined, can interfere with each other, the effect of impact, and even toxicity.

Diabetics suffering from tuberculosis, if a sugar-ling (d860) and isoniazid, rifampicin combination, which will lead to more drug production liver enzyme, a sugar-to accelerate the metabolism and excretion, the deterioration of diabetes, can result in coma , The need to switch to streptomycin, nitrogen thiourea, the amino acid in the treatment of tuberculosis.

People suffering from diabetes, hypertension insulin injections and taking reserpine will hinder the release of norepinephrine, to lower blood sugar, thereby enhancing the role of insulin,出现低血糖response, the switch to Jiangyaling or smell the Indus, Prunella, Siegesbeckiae Grass, chrysanthemums, such as the treatment of hypertension.

Diabetes because of intestinal infection use of chloramphenicol, which can inhibit the activity of liver medicine, oral hypoglycemic agents to slow down the metabolism and easy to cause low blood sugar. According to reports, patients daily oral chloramphenicol two grams, the linked 10 days, will enable the half-life of a sugar-extended from five hours to 15 hours, the blood concentration from every 100 millilitres of 7.5 mg to 14 mg, greatly enhanced A sugar-ling of the hypoglycemic effects and side effects to aggravate deteriorating condition. Therefore, in the use of chloramphenicol, while the need to switch to or hypoglycemic Ling-metformin treatment of diabetic hypoglycemic.

Have coronary-ping (Antuo Ming) and nausea Coke, gifted-down (of antihypertensive drug), Effects of nandrolone, will cause low blood sugar, should avoid sharing.

Diabetes who have sinus tachycardia and hypertension, if glibenclamide and the use of propanolol, glibenclamide the role of strong and fast, propranolol can to increase insulin secretion, will also cover up the heart rate caused by low blood sugar Signs of an increase, it is not appropriate with the service.

Suffering from bronchitis and diabetes patients, if a sugar-and sulfa drugs sulfamethoxazole merger applications will hypoglycemic drug concentration in the blood increase,出现低血糖, it should be between two drug use.

Diabetics suffering from phlebitis, thrombosis, if a sugar-and dicoumarol with clothes and a sugar replacement would prefer the latter, its concentration increases, cause bleeding, while a pair of coumarin can inhibit the sugar - Metabolism and excretion, from its half-life of five hours extended to 18 hours, easy to hypoglycemia. Glibenclamide, chlorine and methyl C gland dicoumarol also combined with a similar situation, it is not appropriate combination.

People suffering from diabetes, rheumatic fever, if aspirin and glibenclamide, a sugar-ling, chlorine, such as methyl hydrazine C combined with aspirin can replacement of oral hypoglycemic agents, to increase blood concentration, Hypoglycemic agents can slow down the metabolism and excretion, Third aspirin itself also has hypoglycemic effect, resulting in hypoglycemia coma, it should switch to naproxen treatment of rheumatism.

In addition, tetracycline and oxytetracycline, gentamycin, kanamycin, and other hypoglycemic Ling combination, can generate a lot of lactic acid and lead to acid poisoning, or even life-threatening, the need to switch to other antibiotics treatment.

Needs to be emphasized is that in diabetes medication, alcohol is harmful, alcoholism drugs inhibit liver enzyme activity, insulin and oral hypoglycemic agents cause severe low blood sawdust, or even death; many times a small amount of alcohol Able to secretion of drugs, hypoglycemic agents speed up the metabolism, reduce the effect. At the same time alcohol metabolites such as the middle of the acetaldehyde by the impact of hypoglycemic agents, can increase concentration in the blood acetaldehyde, a toxic reaction, such as the pulsating headache, nausea and vomiting, sweating thirst, tachycardia, Shortness of breath, blood pressure dropped, even shock, it is necessary Temperance.

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