Individualized treatment of lung cancer

The beginning of a 55-year-old male with chest pain due to Xue Tan, CT examination revealed shadow of the left lung, and the diagnosis of lung cancer at a hospital and the left lower lung resection and mediastinal lymph node dissection, and postoperative pathologic diagnosis was no lymph node metastasis in early lung adenocarcinoma. This is unfortunate in the fortunate because of early surgical treatment of lung cancer effects are rather good. But in the postoperative adjuvant therapy should be carried out which generated intense controversy. One of the view that: Although the patients with early lung cancer, but the pathological type adenocarcinoma, easy transfer of the tendency for insurance purposes, should postoperative chemotherapy and radiotherapy to prevent recurrence and metastasis. The other view is that: Since the early days, and do not superfluous chemotherapy and radiation, not to mention the two treatment is not 100 percent effective. Two views of self, gain pleasure, but also the expense of the patient, how to choose?

This is the medical activities with the arguments and unknowns, the best treatment for cancer, almost unanimous that no more common that the public is justified, said Great Great justified.

Let us look at this case the need for postoperative radiotherapy. Before the 1990s, many doctors to insurance purposes, often for lung cancer patients - whether early or relatively late - after receiving the mediastinal radiotherapy, the purpose is to reduce local recurrence and metastasis to extend patients The survival time. Unfortunately, this goal can not be achieved. Through the integrated high-quality clinical research findings, we were surprised to discover that, for early lung cancer, the old methods of postoperative radiotherapy, can not increase the survival rate, but increased mortality. The cause of death was mainly caused by radiation therapy induced complications. Therefore, in the academic lung cancer has been made such a consensus, for early lung cancer, there is no need to give the old methods of postoperative radiation therapy. Of course, the prerequisite is that these early lung cancer, including the same side in the mediastinal lymph node resection must be clean.

Well chemotherapy?

The so-called chemotherapy is the adoption of several anti-cancer drugs into a certain programme for cancer patients. Because it is intravenous, therefore, the role of drugs is systemic in nature, and this characteristic makes doctors often consider the use of chemotherapy to eliminate or prevent cancer cells specific to the transfer. But until today, a large number of clinical research tells us that the post-operative chemotherapy for early lung cancer patients can only bring minor benefits, we look forward to the chemotherapy drugs significantly reduce or even eliminate cancer cells and the effect of the transfer did not appear. Chemotherapy drugs to patients but the side effects are obvious: hair loss, vicious vomiting, leukopenia, and so on. We must, therefore, in the early postoperative chemotherapy lung cancer to choose between the pros and cons. On the evidence currently available, under normal circumstances does not advocate that the implementation of such patients after chemotherapy.

But the thing is not absolute. Since early lung cancer in general, a slight advantage after chemotherapy, then, whether a minor can these overall benefits of a particular patient pairs into the absolute advantage? If so, how to select patients? How reasonable application of the anti-cancer drugs? Here, it gives us a right of the early lung cancer patients into two serious proposition.

2001, we initiated a research project, is to the nature of lung cancer through research, the number of lung cancer by detecting marked change, and see if you can screen out early recurrence and metastasis of lung cancer in easy, but it is also sensitive to chemotherapy drugs in particular type, which we call the high-risk types of early lung cancer, lung cancer patients to give such postoperative chemotherapy, it may be targeted and not feeling the stones river. Day-to the benefit of chemotherapy tilt direction, we should not hesitate to adjuvant chemotherapy patients. When we can identify early lung cancer in high-risk types of early lung cancer patients after chemotherapy is naturally be doubly cautious.

The tremendous progress of medical science, and has enabled us to early lung cancer after treatment with some new experiment. A step forward in this regard, the most important of just listing of the new drugs in foreign countries "of the Iraqi sand" (Iressa). The role of the drug mechanism completely different from the previous chemotherapy drugs, it will not bring to the patients, such as hair loss and bone marrow transplantation side effects, because it is the role of signal transduction in cells of a particular point, it was known as targeted therapy. Japan and Europe and the United States in the study, even on the sand of Iraq refractory lung cancer can achieve satisfactory results. Application of the former for a period of time, our experience also shows that the Iraq of the sand load on the small tumor patients particularly effective. Therefore, in foreign countries have started to Iraq of sand as postoperative adjuvant treatment of early lung cancer drug clinical research, believe that in the near future, we will find early lung cancer a comprehensive treatment of the most appropriate model.

In this paper, the beginning of the patient, and ultimately did not receive postoperative chemotherapy or radiotherapy. Almost one year has passed, patients and there was no tumor recurrence or metastasis signs of this preliminary prove that the correct treatment. Of course, the final conclusion, to be observed in recent years.

In response to the subject of this paper, lung cancer treatment, is not an easy task, which requires a doctor's knowledge and wisdom, courage, technology, morality and conscience, the need for lung cancer patients and their families the knowledge and understanding of the doctor's cooperation. What better treatment of lung cancer, is not able to speak clearly in a few words, but its basic elements, which is under the stage and physical state to formulate the basic principles of treatment, and then in this framework, according to the will of all patients Comprehensive specific information drawn up after the judgement of the details, this is the treatment of lung cancer - the highest state of individual treatment.